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Nutrient Profile - Molybdenum

What are the benefits of molybdenum?


Molybdenum is an essential trace mineral that plays a crucial role in various bodily functions. Some benefits of molybdenum include:

  1. Enzyme Function: Molybdenum is a component of several enzymes that are involved in important biochemical reactions within the body. For example, it's a cofactor for enzymes involved in breaking down certain amino acids and in the metabolism of drugs and toxins.

  2. Detoxification: Molybdenum contributes to the detoxification process in the body by aiding in the breakdown of sulfites and the metabolism of certain toxins and drugs.

  3. Antioxidant Properties: It acts as a cofactor for the enzyme sulfite oxidase, which helps convert sulfites to sulfates, thereby reducing oxidative stress in the body.

  4. Nitrogen Metabolism: Molybdenum is involved in the conversion of nitrogen to a usable form in plants, which is essential for their growth. In humans, it assists in the metabolism of nitrogen-containing compounds.

  5. Bone Health: While research is ongoing, molybdenum may contribute to bone health by supporting the enzymes involved in bone formation and mineralization.

  6. Dental Health: Molybdenum might play a role in dental health by supporting the prevention of certain dental issues.

It's important to note that the body requires only small amounts of molybdenum, and deficiencies are rare in individuals with a balanced diet. Foods like legumes, grains, nuts, and leafy vegetables are good dietary sources of molybdenum. However, excessive intake of molybdenum from supplements can lead to adverse effects. As with any supplement or mineral, it's advisable to consult a healthcare professional before starting any new supplementation regimen.



What are the differences among the types of molybdenum?


Molybdenum supplements are available in various forms, usually as molybdenum salts or compounds. Some common types of molybdenum supplements include:

  1. Molybdenum Glycinate: This form of molybdenum is bound to the amino acid glycine, which may enhance absorption compared to other forms.

  2. Sodium Molybdate: Sodium molybdate is a common and well-absorbed form of molybdenum found in many supplements. It's a stable compound that provides a source of molybdenum.

  3. Molybdenum Picolinate: This form combines molybdenum with picolinic acid, which is thought to potentially improve absorption in the body.

  4. Molybdenum Citrate: Molybdenum citrate is another form where molybdenum is bound to citric acid, possibly aiding in absorption.

These supplements come in various dosages, typically ranging from micrograms to milligrams, and they should be taken as directed by a healthcare professional or according to the product label.


As with any supplement, it's essential to consult a healthcare provider before starting molybdenum supplementation. They can provide guidance on dosage, potential interactions with medications, and whether you actually need to supplement molybdenum based on your diet and health status. Consuming excessive amounts of molybdenum can lead to adverse effects, so it's crucial to follow recommended dosages.


How much molybdenum is recommended daily?


The recommended dietary allowance (RDA) for molybdenum is as follows:

  • For adults aged 19 years and older: 45 micrograms (mcg) per day

Molybdenum deficiency is rare because it's found in a variety of foods, including legumes, grains, nuts, leafy vegetables, and meats. In most cases, a balanced diet can provide adequate molybdenum to meet daily requirements.


However, certain factors such as gastrointestinal disorders or genetic conditions may interfere with molybdenum absorption, leading to potential deficiency. In such cases, a healthcare professional might recommend supplementation or dietary modifications to ensure adequate intake.


It's important not to exceed the upper limit for molybdenum intake, which is set at 2,000 micrograms per day for adults. Consuming excessive amounts of molybdenum can lead to adverse effects and interfere with the body's ability to absorb other minerals like copper.


As always, before starting any new supplement regimen or significantly altering your diet, it's advisable to consult with a healthcare professional to determine your individual needs and ensure you're consuming a safe and balanced amount of molybdenum.



What are the signs of molybdenum deficiency?


Molybdenum deficiency is rare in humans because the body requires only small amounts of this trace mineral. However, when deficiencies do occur, they might manifest with various symptoms. Some potential signs of molybdenum deficiency include:

  1. Increased sensitivity to sulfites: Molybdenum is involved in the breakdown of sulfites, so deficiency might lead to increased sensitivity to sulfites found in foods, resulting in symptoms like headaches, rapid heartbeat, or skin flushing.

  2. Elevated levels of sulfite or urate in urine: Low molybdenum levels can result in increased excretion of sulfite or urate in urine, which can be detected through laboratory tests.

  3. Reduced enzyme activity: Molybdenum is a cofactor for several enzymes. Deficiency might lead to reduced activity of these enzymes, impacting various metabolic processes.

  4. Impaired sulfur metabolism: Molybdenum plays a role in sulfur metabolism, and deficiency might affect this process, leading to potential symptoms related to sulfur imbalances.

  5. Possible developmental issues: Severe and prolonged molybdenum deficiency might impact growth and development, although this is extremely rare.

It's important to note that these signs are not specific to molybdenum deficiency and can also be caused by other health conditions or deficiencies. If someone suspects a molybdenum deficiency or experiences symptoms that could be related to it, it's crucial to consult a healthcare professional for proper evaluation and diagnosis.



What nutrients can molybdenum interact with?


Molybdenum, when taken in excessive amounts, can potentially interfere with the absorption and metabolism of certain other nutrients, primarily copper.

  1. Copper: High levels of molybdenum might interfere with copper absorption and metabolism. Both minerals compete for absorption in the gastrointestinal tract, and excessive molybdenum intake can reduce copper levels in the body. Copper is an essential mineral involved in various physiological processes, including the formation of red blood cells, connective tissue formation, and proper functioning of the nervous and immune systems.

  2. Sulfur-containing amino acids: Molybdenum is involved in the metabolism of sulfur-containing amino acids like cysteine and methionine. However, excessive molybdenum intake might affect the metabolism of these amino acids, potentially leading to imbalances.

It's important to emphasize that molybdenum interference with other nutrients usually occurs when consumed in very high amounts, well above the recommended dietary intake. For most people who obtain molybdenum from a balanced diet, interference with other nutrients is not a significant concern.


If considering molybdenum supplementation or suspecting high intake through supplements or specific sources, it's advisable to consult with a healthcare professional. They can provide guidance on safe dosages and potential interactions with other nutrients or medications to ensure overall nutritional balance and well-being.

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